Single runes are available anywhere within Diablo 2: Resurrected, beginning in Normal difficulty and moving up the Hell difficulty. Runes can be socketed, similar to gems, which means they can be put into D2R ladder items equipment that is socketed to take advantage of their effects. But the true power of runes is when you put them together in a particular order within an item. Runewords, or runewords as they're referred to are among the most effective items in the game, and are right above the set items and the uniques. The complete list of runewords is available in the following section.
Runes are also used in specific Horadric Cube recipes. For instance, you could mix the Ral rune with an item that is damaged equipment to fix it. This is a fantastic option to use when you're short of gold and don't have the money to make repairs from a vendor. Runes can also be grouped with each other in the Horadric Cube; this is often referred to as "cubing to" and it is a popular method to obtain the next level of rune without needing to hunt for it on the open market. For instance, if you are carrying three El runes, and you need the Eld Rune you can put the three El runes inside the Cube and press the transmute button. Out will come the Eld rune. This recipe for upgrading is available in the rune chart below.
The quest for Hellforge within Act 4 will always drop some runes. It is frequently used to pay to speed up the scenes. The Countess, located in the lower part of the Forgotten Tower in Act 1's Black Marsh, is another excellent source of runes.Because they have a certain of rarities, ranging from the most popular (El) through to D2R items cheap the most rare (Zod) They are often employed as an economy in Diablo 2. El and Lem are typically considered to be low runes. Pul and Gul are usually considered to be mid runes, while Vex to Zod are typically considered to be high runes. If you come across high or mid runes during your travels, make sure not to sell the runes easily!